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Request for Information – Prophylactic Platform for Medical Countermeasures

Federal · Portfolio Management Executive for Chemical, Biological, Radiological and Nuclear Defense (PME CBRND)Due Wednesday, November 18, 2026
Client
Portfolio Management Executive for Chemical, Biological, Radiological and Nuclear Defense (PME CBRND)
Solicitation No.
W911SR-26-S-PPFC
Posted
10/19/2026
Category
US Federal
Budget
—
NAICS
541715
Set-aside
No Set aside used
Contact
Scott Hoffman

Description

AI Generated

The Chemical, Biological, Radiological, Nuclear Medical - Accelerated Defense Pharmaceuticals program seeks information regarding advanced prophylactic platform technologies directed against specific chemical, biological, radiological, and nuclear threats. The buyer needs information on the design, manufacturing, non-clinical testing, and clinical testing of candidates to progress existing platforms toward Phase I or Phase II clinical trials regulatory and operational milestones. Qualified commercial and academic product developers are eligible to submit responses. Interested parties must email their submissions as a single searchable PDF document of up to four pages in total, adhering to strict margin and font guidelines. Respondents must include corporate experience, indicative high-level timelines, and high-level Rough Order of Magnitude budgetary cost bands.

Key solicitation details

AI-extracted from RFI Prophylactic Platform Technologies for Medical Countermeasures_19Oct2026.pdf, Appendix 2_Draft_Description_Statement_of_Objectives_19Oct2026.pdf. Confirm against the original documents before bidding.

This Request for Information seeks input from qualified commercial and academic product developers regarding advanced prophylactic platform technologies directed against specific CBRN threats. The goal is to accelerate innovation and progress existing candidate platforms toward Phase I or Phase II clinical trial milestones. Qualified commercial and academic product developers with mature or proven platform technologies are eligible to respond.

Issued by
Portfolio Management Executive for Chemical, Biological, Radiological and Nuclear Defense (PME CBRND)
How to submit
Electronic via email
Submission details
Submit a single searchable PDF document to the Government Points of Contact with subject line 'RFI Response: PME CBRND JPM CBRN Medical ADP - [Organization Name]'. Core capability description limited to 4 pages (12-point font, 1-inch margins), plus an optional 1-page cover page.
Contract term
up to four (4) years from date of award
Place of performance
Primary place of performance will be the contractors' facilities

How proposals are evaluated

Performer Past FDA Experience
Performer Past Experience

Scope of work

  • Design, manufacture, non-clinical, and clinical testing of prophylactic platform technology for CBRN threats
  • Formulate final prototype candidate products for clinical evaluation
  • Manufacture and release cGMP prototype products for clinical trial use
  • Regulatory interactions and filing of Investigational New Drug (IND) applications
  • Generation of Regulatory Strategy and Target Product Profile documents
  • Delivery of monthly technical and financial reports, spend plans, and progress schedules
  • Draft and final non-clinical and clinical study reports

Minimum qualifications

  • Demonstrated, successful history of designing, manufacturing, and clinical testing of prophylactic MCM platforms

Documents to include with the bid

  • Cover page
  • Prophylactic Platform Technology Capability Description

Official SAM.gov notice

Solicitation number
W911SR27SPPFC
Agency
Department of Defense
Buying office
Dept of the Army › W6QK ACC-APG
Notice type
Special Notice
Responses due
Nov 18, 2026, 4:30 PM ET
Posted on SAM.gov
Oct 19, 2026
NAICS
541715 · Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
Product/service code
AC15
Set-aside
No Set aside used
Place of performance
Frederick, MD, 21702
Contracting contact
Scott Hoffman
scott.i.hoffman2.civ@army.mil
Additional contact
Alexander Mayatte
alexander.z.mayatte.civ@army.mil
Read the official notice description

The Capability Program Executive for Chemical, Biological, Radiological and Nuclear Defense (CPE CBRND), Medical - Accelerated Defense Pharmaceuticals program is formally requesting information from capable companies. The objective of the program is to progress the development of existing prophylactic MCMs manufactured on existing platform technologies that support clinical safety and/or possess strong preclinical immunogenicity, safety, and efficacy data.

Source: SAM.gov contract opportunities data (U.S. federal public data).

Incumbent

No incumbent history found for this requirement. The notice does not cite a current contract, and no earlier award from this buying office matches it.

Market context

Awards in the same category (Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)). This is not this requirement's award history.

Recent similar awards: Department of Defense, NAICS 541715, performed in MD

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NORTHROP GRUMMAN SYSTEMS CORPORATIONFA237726CB034 · COMBAT IDENTIFICATION AUTOMATED TARGET RECOGNITION TECHNOLOGIES (CATCH) CALL 06$1.0MOct 17, 2031
APPLIED RESEARCH ASSOCIATES, INC.W911QX26CA007 · ENGINEERING AND ANALYSIS SUPPORT FOR THE DEVELOPMENT OF THE ADVANCED JOINT EFFECTIVENESS M$478.6KSep 1, 2031
THE JOHNS HOPKINS UNIVERSITY APPLIED PHYSICS LABORATORY LLCFA865626FB009 · AIR WARFARE SYSTEMS$1.5MJul 31, 2031
THE SURVICE ENGINEERING COMPANY LLCW911QX26FA026 · ARMY RESEARCH, TECHNICAL AND ENGINEERING SERVICES (ARTES)$10.9MJun 30, 2031
CARDINAL ENGINEERING, LLCN0001425C1303 · PERFORM INVESTIGATION, DEVELOPMENT, AND DEMONSTRATION OF POWER AND ENERGY FOCUS AREA SOLUT$4.1MJun 15, 2031

Top vendors in this category: Department of Defense, NAICS 541715, since Oct 1, 2024

22,948 contract awards in this NAICS over the period.

  1. 1. LOCKHEED MARTIN CORPORATION$5.3B
  2. 2. FLUOR MARINE PROPULSION, LLC$4.2B
  3. 3. LOCKHEED MARTIN CORP$3.8B
  4. 4. THE JOHNS HOPKINS UNIVERSITY APPLIED PHYSICS LABORATORY LLC$3.0B
  5. 5. THE AEROSPACE CORPORATION$2.2B

Source: USAspending.gov federal award data (U.S. federal public data). A contract is called the incumbent only when the notice or its documents cite it by number.

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Document check

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3 available filesDocuments checked

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