RFI for Artificial Intelligence-Enabled Discovery of Broad-Spectrum Small-Molecule Inhibitors for Filoviruses Service

The Defense Threat Reduction Agency is conducting market research to identify organizations with capabilities in artificial intelligence for application in the discovery and advancement of broad-spectrum, small-molecule therapeutics targeting filoviruses. The agency is seeking to solve the challenge of rapidly identifying and developing effective countermeasures against these viral threats. The scope of work covers artificial intelligence-driven design, in vitro verification of hits, and early preclinical proof-of-concept evaluation. Only organizations based in the United States are eligible to participate in this market research opportunity. The performing organization will conduct all requested work offsite. The agency has not disclosed a specific budget and is currently looking for proposals to determine cost parameters. No key dates or deadlines are specified in the current announcement.