Advanced Postdoctoral Career Transition Awards Services

The National Institutes of Health, or a related federal health agency, is seeking advanced postdoctoral career transition awards services to promote diversity in the translational research workforce for Alzheimer's disease and Alzheimer's disease-related dementias, including frontotemporal dementia, Lewy body dementia, and vascular dementia. The agency aims to support highly trained translational researchers as they transition to research independence in the field of Alzheimer's disease and Alzheimer's disease-related dementias. This initiative intends to expand the pool of translational researchers who can effectively participate in and lead a team-science, precision medicine approach to studies of disease treatment, prevention, early detection, and disease management and care. The scope of work requires applying various aspects of data science, such as genomics, proteomics, metabolomics, computational biology, bioinformatics, mathematics, engineering, and biostatistics, to Alzheimer's disease, Alzheimer's disease-related dementias, and neurodegenerative research. The selected provider must translate principles and research findings from behavioral and social research into the development of individual, population, and system-level interventions aimed at reducing dementia risk, preventing cognitive decline and dementia, and improving the health and well-being of persons living with dementia and their caregivers. Additionally, the project covers obtaining skills in traditional and emerging drug discovery and drug development, including medicinal chemistry, high-throughput screening, quantitative pharmacology, toxicology, and clinical trial design. The work also involves conducting cross-national dementia research using harmonized data on cognitive function to identify potential modifiable causal drivers of dementia risk and resilience. Eligible organizations must be located onshore within the United States. The agency requires the performance of the work to be conducted offsite. The agency has not disclosed a specific budget and is looking for proposals to determine the cost. Key dates and specific evaluation criteria are not specified in the initial solicitation details.