Write 1 complete proposal every month, free.

Sources SoughtSolicitation ACQ-27-0065

USPTO Biosequence Search System Market Research and Vendor Engagement

Submission deadlineNov 17, 2026See documents for time and submission instructions
0 of 5 free RFP views today
FREE AI PROPOSAL WRITING

Write a proposal for this RFP.Start free in one click.

1 proposal a month on Free · No credit card requiredCreate a free account to continue with this RFP.

Team preparing a proposal together
This RFP. Your next proposal.Analyze the requirements. Build your outline. Write with AI.

About this opportunity

AI summary

The United States Patent and Trademark Office is conducting market research to identify commercially available, turnkey solutions for searching biological sequences and prior art claimed in patent applications. The agency seeks a next-generation system utilizing Super Intelligence-assisted capabilities to improve search quality and efficiency during patent examinations, as detailed in the draft Statement of Objectives. Only vendors responding to this Request for Information will be eligible for consideration to compete as prime offerors in a contemplated alternative competition. Interested respondents must complete Attachment 1, answering questions 1 through 6, and demonstrate that their offerings qualify as commercial products and services under FAR Part 2. Questions are due via email using Attachment 3 by 12:00 PM ET on November 6, 2026. Final RFI responses must be emailed to [email protected] and [email protected] by 12:00 PM ET on November 17, 2026.

Scope of work

  • End-to-end biosequence search and alignment software and platform
  • Patent document ingestion of claims, specifications, and sequence listings
  • Comprehensive one-to-one nucleotide and protein alignment searching using standard algorithms
  • Complex search enablement including fragments, patterns, regular expressions, and reverse complements
  • Super Intelligence-assisted search strategy generation and sequence feature extraction
  • Super Intelligence-driven search result assessment, clustering, and prioritization
  • Human-in-the-loop feedback mechanisms preserving audit trails
  • Modular, cloud-native bioinformatics platform deployed in USPTO AWS cloud

Minimum qualifications

  • Solution and services must meet the definition of commercial products and services under FAR Part 2

Documents to include with your response

  • RFI Attachment 1 – RFI Response Template (completed Corporate Profile and responses to Q.1-6)

Key dates

Questions due
no later than 12:00 PM ET on November 6, 2026
RFI responses due
no later than 12:00 PM ET on November 17, 2026
Anticipated Phase 2 product demonstrations
between December 1, 2026 and January 15, 2027

How to submit

Method
Email
Instructions
Submit completed Attachment 1 – RFI Response Template only via email to designated contacts with subject 'Biosequence PTAG RFI Response - Company Name'. No additional marketing materials.

Contract details

Place of performance
USPTO-hosted AWS cloud environment

Federal notice details

Solicitation number
ACQ-27-0065
Agency
Department of Commerce
Buying office
US Patent and Trademark Office › Dept of Commerce PTO
Notice type
Sources Sought
Responses due
Nov 17, 2026, 12:00 PM ET
Posted on SAM.gov
Nov 4, 2026
NAICS
518210 · Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services
Product/service code
DH10
Set-aside
No Set aside used
Place of performance
Alexandria, VA, 22313
Contracting contact
Whitney Lee
Whitney.Lee@uspto.gov
5712727328
Additional contact
Brian Carper
brian.carper@uspto.gov
5712721665
View official notice on SAM.gov

Source: SAM.gov. Read the official notice for the complete description and current instructions.

Incumbent and award research

No incumbent history found for this requirement. The notice does not cite a current contract, and no earlier award from this buying office matches it.

Market context

Awards in the same category (Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services). This is not this requirement's award history.

Recent similar awards: Department of Commerce, NAICS 518210, performed in VA

Vendor and awardValueEnds
SPIRE GLOBAL SUBSIDIARY, INC.1332KP26F0082 · SPACE-BASED ENVIRONMENTAL MONITORING (SBEM) PROTECH 2.0 TASK ORDER 1 (TO1):IN THIS TASK OR$16.6MDec 1, 2028
MODUS EDISCOVERY, INC.1333BJ26F00282066 · E-DISCOVERY SOFTWARE SYSTEM - CLOUD (EDSS-C)$119.0KSep 28, 2027
LHDTSV LLC1333BJ21C00150003 · PATENT TECHNICAL SERVICES COMPETITION FOR A CONTRACT AWARD OF A BASE PERIOD AND 4 OPTIONAL$128.4MMar 29, 2027
PERATON INC.1333BJ25C00280001 · STORAGE INFRASTRUCTURE MANAGED SERVICES (SIMS)$38.3MDec 6, 2026
SPIRE GLOBAL SUBSIDIARY, INC.1332KP25F0062 · TO ACQUIRE 3000 NEAR-REAL-TIME GLOBAL NAVIGATION SATELLITE SYSTEM (GNSS) RADIO OCCULTATION$11.2MSep 18, 2026

Top vendors in this category: Department of Commerce, NAICS 518210, since Oct 1, 2024

137 contract awards in this NAICS over the period.

  1. 1. KBR WYLE SERVICES, LLC$67.9M
  2. 2. SPACE SCIENCES AND ENGINEERING LLC$41.2M
  3. 3. LHDTSV LLC$38.6M
  4. 4. PERATON INC.$38.3M
  5. 5. SPIRE GLOBAL SUBSIDIARY, INC.$33.7M

Source: USAspending.gov federal award data (U.S. federal public data). A contract is called the incumbent only when the notice or its documents cite it by number.

PRODUCT DEMO

How AI proposal writing works.

Analyze the RFP, build an outline, write and submit.

CRAXY AI IN ACTION — example proposal

Make a more informed bid decision.

Analyze the solicitation against your company profile. See your matching score, strengths, risks and the submission checklist before investing in a response.

Start my proposal freeActual product screens · Example proposal
AI PROPOSAL WRITING

Write your response to this RFP.

Create a draft using the solicitation and your company documents.

Start my proposal free1 proposal a month on Free · No credit card required