What the buyer needs
AI summaryThe Advanced Research Projects Agency for Health is seeking proposals to support the Brain Repair of Any Injured Neural Structure Exploratory Topic program. The agency is hosting a virtual Proposers' Day on June 9, 2026, to foster a greater understanding of this program, with a recording to be made available on the program website. Interested parties must review the BRAINS Special Notice ARPA-H-SN-26-153 and the Innovative Solutions Opening ARPA-H-SOL-26-148. The agency requires all interested parties to submit a mandatory solution summary prior to submitting a full proposal. The agency will not make any awards or provide any funding as a direct result of these solution summary submissions. The agency anticipates making multiple awards using Other Transaction award types resulting from the subsequent solicitation.
Scope of work
- TA1: Defining and generating precursor tissue for any brain region other than neocortex or spinal cord
- Characterizing natural precursor tissue including cell types, density, spatial organization, and non-cellular components
- Establishing protocols for generating human iPSC-derived precursor cells
- Elaborating detailed tissue generation methods and producing prototype precursor tissue
- TA2: Optimizing surgical engraftment of precursor tissue into adult brains in animal models
- Establishing surgical transplantation methods using fetal non-human donor into conspecific host
- Demonstrating grafted donor tissue survival and vascularization within 48 hours of transplantation
- Demonstrating grafted donor tissue in situ maturation, internal structure, and target connections
Minimum qualifications
- Participation restricted to potential proposer community (not intended for patients, patient advocates, media or general interest audience)
Documents to include with your response
- Solution summary
How to submit
- Method
- Electronic via registration portal
- Instructions
- Advance registration required online at http://solutions.arpa-h.gov/Events/BRAINS. Mandatory solution summary submission required for subsequent ISO ARPA-H-SOL-26-148.
Incumbent and award research
No incumbent history found for this requirement. The notice does not cite a current contract, and no earlier award from this buying office matches it.
Market context
Awards in the same category (Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)). This is not this requirement's award history.
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Source: USAspending.gov federal award data (U.S. federal public data). A contract is called the incumbent only when the notice or its documents cite it by number.